As soybean processing expands in North Dakota, opportunities arise to use soybean byproducts as practical and effective dietary supplements for cattle. There is significant potential to increase the retention of calves after weaning, adding value by utilizing local feed resources such as forages, oilseed, and grain byproducts during backgrounding programs. These programs prepare calves for grain-based finishing, where growth and feed efficiency are critical, particularly under winter feeding conditions when protein supplementation plays a vital role. This study evaluates soy-based and dried corn distillers grains with solubles (DDGS)-based supplements, processed as cubes or meals, to assess their impact on cattle backgrounding performance. Preliminary results from our previous NDSC-funded research, suggest pelleted soybean-based supplement enhance nutrient digestibility, indicating advantages in nutrient utilization and feed efficiency. Building on these findings, this project will assess growth performance, feed efficiency and nutrient utilization in calves fed these supplements in a backgrounding system. This study aims to optimize nutrient use, reduce losses, and enhance fiber digestibility. Additionally, ruminal in situ approaches will be used from samples collected from the previous study to clarify how cubes vs. meal affect nutrient digestion. The results of this research will provide North Dakota producers with data-driven insights to optimize supplementation practices, support the utilization of local soybean products, and enhance profitability for both crop and livestock farmers. Ultimately, the development of effective soybean-based supplements can strengthen the connection between the crop and cattle industries, fostering a more integrated and sustainable agricultural system.