The recent introduction of the guava root knot nematode, Meloidogyne enterolobii, to North Carolina threatens profitable soybean production in this state. Currently,8counties have been confirmed with this nematode, and a separate survey to identify counties with this nematode is ongoing. This nematode is significantly more aggressive than the other root knot nematode species found in NC, and rapidly reproduces, causing damaging populations. Additionally, this nematode has a wide host range that affects numerous weed species and several rotational crops, including vegetable crops, sweet potatoes, and tobacco. Chemical controls for general nematode control in soybean are limited due to the costs of application and the limited economic return with their application. Identification of varietal resistance is important to continue to economically produce soybean, with this pest continuing to spread in North Carolina. This project identified several varieties with low reproduction of M. enterolobii, which may lead to improved management recommendations.